Pseudomonas aeruginosa PAO1, PA0017

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0017
Name
Synonym: fmu
Synonym: sun
Replicon chromosome
Genomic location 18767 - 20071 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248707.1
GI 15595215
Affymetrix PA0017_at
DNASU PaCD00006010
Entrez 879297
GenBank AAG03407.1
INSDC AAG03407.1
NCBI Locus Tag PA0017
protein_id(GenBank) gb|AAG03407.1|AE004441_8|gnl|PseudoCAP|PA0017
TIGR NTL03PA00018
UniParc UPI00000C4EEC
UniProtKB Acc Q9I7A9
UniProtKB ID RSMB_PSEAE
UniRef100 UniRef100_Q9I7A9
UniRef50 UniRef50_Q9I7A9
UniRef90 UniRef90_Q9I7A9

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 5.15
Kyte-Doolittle Hydrophobicity Value -0.185
Molecular Weight (kDa) 47.2
Isoelectric Point (pI) 8.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 581 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000017 (561 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0017

Human Homologs

Ensembl 86, assembly GRCh38.p7
NOP2 nucleolar protein [Source:HGNC Symbol;Acc:HGNC:7867]
E-value: 1.9e-26
Percent Identity: 29.0

References

NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.
Schlösser A, Hamann A, Bossemeyer D, Schneider E, Bakker EP
Mol. Microbiol. 1993 Aug;9(3):533-43
PubMed ID: 8412700
Cloning of the trkAH gene cluster and characterization of the Trk K(+)-uptake system of Vibrio alginolyticus.
Nakamura T, Yamamuro N, Stumpe S, Unemoto T, Bakker EP
Microbiology (Reading, Engl.) 1998 Aug;144 ( Pt 8)
PubMed ID: 9720051