Pseudomonas aeruginosa UCBPP-PA14, PA14_01010 (hsiB1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_01010
Name
hsiB1
Synonym: tssB1
Replicon chromosome
Genomic location 98900 - 99418 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq YP_788240.1
GI 116053803
Entrez 4383501
INSDC ABJ15039.1
NCBI Locus Tag PA14_01010
UniParc UPI00000C4F24
UniProtKB Acc Q02UZ6
UniProtKB ID Q02UZ6_PSEAB
UniRef100 UniRef100_W0YKW6
UniRef50 UniRef50_J2YIR2
UniRef90 UniRef90_J2YIR2

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiB1
Product Name Confidence: Class 1
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)
Evidence for Translation
Charge (pH 7) -3.00
Kyte-Doolittle Hydrophobicity Value -0.251
Molecular Weight (kDa) 18.8
Isoelectric Point (pI) 4.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4UQZ PROTEIN TRANSPORT 06/25/14 Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes PSEUDOMONAS AERUGINOSA PAO1 1.599 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 107 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000082 (1276 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01010
Search term: hsiB1
Search term: HsiB1

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999