Pseudomonas aeruginosa UCBPP-PA14, PA14_45000 (gcl)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_45000
Name	gcl
Replicon	chromosome
Genomic location	4012138 - 4013913 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	3 transposon mutants in orthologs

Cross-References

RefSeq	YP_791751.1
GI	116049446
EC Number	4.1.1.47
Entrez	4383168
INSDC	ABJ10682.1
NCBI Locus Tag	PA14_45000
UniParc	UPI0000E44B17
UniProtKB Acc	Q02JY5
UniProtKB ID	Q02JY5_PSEAB
UniRef100	UniRef100_W0YM09
UniRef50	UniRef50_P0AEP8
UniRef90	UniRef90_Q9I3L0

Product

Feature Type	CDS
Coding Frame	1
Product Name	glyoxylate carboligase
Synonyms
Evidence for Translation
Charge (pH 7)	-13.82
Kyte-Doolittle Hydrophobicity Value	0.015
Molecular Weight (kDa)	64.4
Isoelectric Point (pI)	5.27

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 594 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003851 (499 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_45000 Search term: gcl Search term: glyoxylate carboligase

Human Homologs

Ensembl 110, assembly GRCh38.p14

ENSP00000323811 2-hydroxyacyl-CoA lyase 1 [Source:HGNC Symbol;Acc:HGNC:17856] E-value: 1.0e-32 Percent Identity: 24.0

References