Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA0796
|
Name |
prpB
Synonym: bcpA |
Replicon | chromosome |
Genomic location | 874206 - 875102 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
RefSeq | NP_249487.1 |
GI | 15595993 |
Affymetrix | PA0796_prpB_at |
Entrez | 882026 |
GenBank | AAG04185.1 |
INSDC | AAG04185.1 |
NCBI Locus Tag | PA0796 |
protein_id(GenBank) | gb|AAG04185.1|AE004515_1|gnl|PseudoCAP|PA0796 |
TIGR | NTL03PA00797 |
UniParc | UPI00000C5159 |
UniProtKB Acc | Q9I5E2 |
UniProtKB ID | Q9I5E2_PSEAE |
UniRef100 | UniRef100_W0YNY4 |
UniRef50 | UniRef50_Q56062 |
UniRef90 | UniRef90_W0YNY4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
carboxyphosphonoenolpyruvate phosphonomutase
|
Synonyms |
CPEP phosphonomutase |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -5.92 |
Kyte-Doolittle Hydrophobicity Value | 0.032 |
Molecular Weight (kDa) | 32.1 |
Isoelectric Point (pI) | 5.20 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6T4V | LYASE | 10/15/19 | Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in apo form. | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.807 | X-RAY DIFFRACTION | 100.0 |
6T5M | LYASE | 10/16/19 | Crystal structure of 2-methylisocitrate lyase (PrpB) from Pseudomonas aeruginosa in complex with Mg(II)-pyruvate. | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 1.76 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 343 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000769 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA0796
Search term: prpB
Search term: carboxyphosphonoenolpyruvate phosphonomutase
|
Cloning, overexpression and mechanistic studies of carboxyphosphonoenolpyruvate mutase from Streptomyces hygroscopicus.
Pollack SJ, Freeman S, Pompliano DL, Knowles JR
Eur J Biochem 1992 Oct 15;209(2):735-43
PubMed ID: 1330557
|
Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon.
Horswill AR, Escalante-Semerena JC
J Bacteriol 1997 Feb;179(3):928-40
PubMed ID: 9006051
|