Pseudomonas aeruginosa PAO1, PA1384 (galE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1384
Name
galE
Replicon chromosome
Genomic location 1503568 - 1504581 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_250075.1
GI 15596581
Affymetrix PA1384_galE_at
DNASU PaCD00006638
Entrez 878496
GenBank AAG04773.1
INSDC AAG04773.1
NCBI Locus Tag PA1384
protein_id(GenBank) gb|AAG04773.1|AE004568_2|gnl|PseudoCAP|PA1384
TIGR NTL03PA01385
UniParc UPI00000C534E
UniProtKB Acc Q9I3W0
UniProtKB ID Q9I3W0_PSEAE
UniRef100 UniRef100_Q9I3W0
UniRef50 UniRef50_A1V1F5
UniRef90 UniRef90_A0A080VM56

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-glucose 4-epimerase
Product Name Confidence: Class 2
Synonyms galactowaldenase
Evidence for Translation
Charge (pH 7) -3.72
Kyte-Doolittle Hydrophobicity Value 0.016
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 642 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001310 (244 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1384
Search term: galE

Human Homologs

Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 1.1e-100
Percent Identity: 54.0
Ensembl 110, assembly GRCh38.p14
UDP-galactose-4-epimerase [Source:HGNC Symbol;Acc:HGNC:4116]
E-value: 1.1e-100
Percent Identity: 54.0

References

Nucleotide sequences of the gal E gene and the gal T gene of E. coli.
Lemaire HG, Müller-Hill B
Nucleic Acids Res 1986 Oct 10;14(19):7705-11
PubMed ID: 3022232
Genetics of galactose metabolism of Erwinia amylovora and its influence on polysaccharide synthesis and virulence of the fire blight pathogen.
Metzger M, Bellemann P, Bugert P, Geider K
J Bacteriol 1994 Jan;176(2):450-9
PubMed ID: 7507102
The gene cluster directing O-antigen biosynthesis in Yersinia enterocolitica serotype 0:8: identification of the genes for mannose and galactose biosynthesis and the gene for the O-antigen polymerase.
Zhang L, Toivanen P, Skurnik M
Microbiology (Reading) 1996 Feb;142 ( Pt 2):277-288
PubMed ID: 8932701