Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1674
|
Name |
folE2
|
Replicon | chromosome |
Genomic location | 1825495 - 1826040 (- strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250365.1 |
GI | 15596871 |
Affymetrix | PA1674_folE2_at |
Entrez | 879308 |
GenBank | AAG05063.1 |
INSDC | AAG05063.1 |
NCBI Locus Tag | PA1674 |
protein_id(GenBank) | gb|AAG05063.1|AE004595_2|gnl|PseudoCAP|PA1674 |
TIGR | NTL03PA01675 |
UniParc | UPI000012B278 |
UniProtKB Acc | Q9I351 |
UniProtKB ID | GCH12_PSEAE |
UniRef100 | UniRef100_Q9I351 |
UniRef50 | UniRef50_Q2JPT8 |
UniRef90 | UniRef90_Q9I351 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
GTP cyclohydrolase I precursor
|
Synonyms | |
Evidence for Translation |
Detected using LC-MS/MS (20.24 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 1.10 |
Kyte-Doolittle Hydrophobicity Value | -0.043 |
Molecular Weight (kDa) | 20.2 |
Isoelectric Point (pI) | 7.56 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 471 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003716 (533 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1674
Search term: folE2
Search term: GTP cyclohydrolase I precursor
|
Ensembl
110, assembly
GRCh38.p14
|
GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193]
E-value:
1.2e-56
Percent Identity:
56.7
|
Ensembl
110, assembly
GRCh38.p14
|
GTP cyclohydrolase 1 [Source:HGNC Symbol;Acc:HGNC:4193]
E-value:
1.2e-56
Percent Identity:
56.7
|
Cloning and sequencing of cDNA encoding rat GTP cyclohydrolase I. The first enzyme of the tetrahydrobiopterin biosynthetic pathway.
Hatakeyama K, Inoue Y, Harada T, Kagamiyama H
J Biol Chem 1991 Jan 15;266(2):765-9
PubMed ID: 1985963
|
Allosteric characteristics of GTP cyclohydrolase I from Escherichia coli.
Schoedon G, Redweik U, Frank G, Cotton RG, Blau N
Eur J Biochem 1992 Dec 1;210(2):561-8
PubMed ID: 1459137
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|