Pseudomonas aeruginosa PAO1, PA1737

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1737
Name
Synonym: fadB
Replicon chromosome
Genomic location 1880199 - 1882343 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250428.1
GI 15596934
Affymetrix PA1737_at
Entrez 878600
GenBank AAG05126.1
INSDC AAG05126.1
NCBI Locus Tag PA1737
protein_id(GenBank) gb|AAG05126.1|AE004600_2|gnl|PseudoCAP|PA1737
TIGR NTL03PA01738
UniParc UPI00000C546E
UniProtKB Acc Q9I300
UniProtKB ID Q9I300_PSEAE
UniRef100 UniRef100_S0IDW6
UniRef50 UniRef50_H6RWW7
UniRef90 UniRef90_A0A022PB23

Product

Feature Type CDS
Coding Frame 1
Product Name
probable 3-hydroxyacyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.73
Kyte-Doolittle Hydrophobicity Value -0.011
Molecular Weight (kDa) 76.7
Isoelectric Point (pI) 6.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 479 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003654 (410 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1737

Human Homologs

Ensembl 110, assembly GRCh38.p14
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha [Source:HGNC Symbol;Acc:HGNC:4801]
E-value: 2.6e-94
Percent Identity: 33.4

References

No references are associated with this feature.