Pseudomonas aeruginosa PAO1, PA1772

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1772
Name
Synonym: menG
Replicon chromosome
Genomic location 1917599 - 1918087 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250463.1
GI 15596969
Affymetrix PA1772_at
Entrez 880779
GenBank AAG05161.1
INSDC AAG05161.1
NCBI Locus Tag PA1772
protein_id(GenBank) gb|AAG05161.1|AE004603_1|gnl|PseudoCAP|PA1772
TIGR NTL03PA01773
UniParc UPI000012EF00
UniProtKB Acc Q9I2W7
UniProtKB ID RRAAH_PSEAE
UniRef100 UniRef100_B7VBA7
UniRef50 UniRef50_Q8EE23
UniRef90 UniRef90_C1DHC2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable methyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by iTRAQ (PMID:21863142).
Charge (pH 7) -6.62
Kyte-Doolittle Hydrophobicity Value -0.011
Molecular Weight (kDa) 17.4
Isoelectric Point (pI) 4.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3C8O HYDROLASE REGULATOR 02/12/08 The Crystal Structure of RraA from PAO1 Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 251 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003623 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1772

Human Homologs

References

Menaquinone biosynthesis: conversion of o-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid and menaquinones by Escherichia coli extracts.
Bryant RW Jr, Bentley R
Biochemistry 1976 Nov 2;15(22):4792-6
PubMed ID: 791360
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142