Pseudomonas aeruginosa PAO1, PA1971 (braZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1971
Name
braZ
Replicon chromosome
Genomic location 2151755 - 2153068 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_250661.1
GI 15597167
Affymetrix PA1971_braZ_at
Entrez 879216
GenBank AAG05359.1
INSDC AAG05359.1
NCBI Locus Tag PA1971
protein_id(GenBank) gb|AAG05359.1|AE004623_9|gnl|PseudoCAP|PA1971
TIGR NTL03PA01971
UniParc UPI0000126ABD
UniProtKB Acc P25185
UniProtKB ID BRAZ_PSEAE
UniRef100 UniRef100_P25185
UniRef50 UniRef50_P19072
UniRef90 UniRef90_P25185

Product

Feature Type CDS
Coding Frame 1
Product Name
branched chain amino acid transporter BraZ
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 8.41
Kyte-Doolittle Hydrophobicity Value 1.110
Molecular Weight (kDa) 45.3
Isoelectric Point (pI) 8.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 131 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003462 (814 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1971
Search term: braZ

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Isolation of the braZ gene encoding the carrier for a novel branched-chain amino acid transport system in Pseudomonas aeruginosa PAO.
Hoshino T, Kose-Terai K, Uratani Y
J Bacteriol 1991 Mar;173(6):1855-61
PubMed ID: 1900503