Pseudomonas aeruginosa PAO1, PA2086

Gene Feature Overview

Strain	Pseudomonas aeruginosa PAO1 (Stover et al., 2000) GCF_000006765.1|latest
Locus Tag	PA2086
Name
Replicon	chromosome
Genomic location	2295533 - 2296435 (+ strand)
Transposon Mutants in orthologs	1 transposon mutants in orthologs

Cross-References

RefSeq	NP_250776.1
GI	15597282
Affymetrix	PA2086_at
Entrez	882121
GenBank	AAG05474.1
INSDC	AAG05474.1
NCBI Locus Tag	PA2086
protein_id(GenBank)	gb|AAG05474.1|AE004636_5|gnl|PseudoCAP|PA2086
TIGR	NTL03PA02086
UniParc	UPI00000C5595
UniProtKB Acc	Q9I229
UniProtKB ID	Q9I229_PSEAE
UniRef100	UniRef100_Q9I229
UniRef50	UniRef50_I4KTP8
UniRef90	UniRef90_V6AGL6

Product

Feature Type	CDS
Coding Frame	1
Product Name	probable epoxide hydrolase Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7)	-5.69
Kyte-Doolittle Hydrophobicity Value	-0.231
Molecular Weight (kDa)	33.5
Isoelectric Point (pI)	6.27

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4BAT	HYDROLASE	09/16/12	Structure of a putative epoxide hydrolase t131d mutant from Pseudomonas aeruginosa.	PSEUDOMONAS AERUGINOSA PAO1	1.3	X-RAY DIFFRACTION	99.7
4BB0	HYDROLASE	09/17/12	Structure of a putative epoxide hydrolase Q244E mutant from Pseudomonas aeruginosa, with bound MFA.	PSEUDOMONAS AERUGINOSA PAO1	1.77	X-RAY DIFFRACTION	99.7
4BAZ	HYDROLASE	09/17/12	Structure of a putative epoxide hydrolase Q244E mutant from Pseudomonas aeruginosa.	PSEUDOMONAS AERUGINOSA PAO1	1.35	X-RAY DIFFRACTION	99.7
4BAU	HYDROLASE	09/16/12	Structure of a putative epoxide hydrolase t131d mutant from Pseudomonas aeruginosa, with bound MFA	PSEUDOMONAS AERUGINOSA PAO1	1.55	X-RAY DIFFRACTION	99.7
4B9E	HYDROLASE	09/04/12	Structure of a putative epoxide hydrolase from Pseudomonas aeruginosa, with bound MFA.	PSEUDOMONAS AERUGINOSA PAO1	1.4	X-RAY DIFFRACTION	100.0
4B9A	HYDROLASE	09/03/12	Structure of a putative epoxide hydrolase from Pseudomonas aeruginosa.	PSEUDOMONAS AERUGINOSA PAO1	1.45	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 388 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003369 (365 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2086 Search term: probable epoxide hydrolase

Human Homologs

References

Lack of homology between two haloacetate dehalogenase genes encoded on a plasmid from Moraxella sp. strain B. Kawasaki H, Tsuda K, Matsushita I, Tonomura K J Gen Microbiol 1992 Jul;138(7):1317-23 PubMed ID: 1512562