Pseudomonas aeruginosa PAO1, PA2125

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2125
Name
Replicon chromosome
Genomic location 2337868 - 2339316 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250815.1
GI 15597321
Affymetrix PA2125_at
Entrez 878590
GenBank AAG05513.1
INSDC AAG05513.1
NCBI Locus Tag PA2125
protein_id(GenBank) gb|AAG05513.1|AE004640_2|gnl|PseudoCAP|PA2125
TIGR NTL03PA02125
UniParc UPI00000C55BC
UniProtKB Acc Q9I1Z0
UniProtKB ID Q9I1Z0_PSEAE
UniRef100 UniRef100_K1DWB7
UniRef50 UniRef50_L9PMM6
UniRef90 UniRef90_A0A077K1H8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable aldehyde dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -7.08
Kyte-Doolittle Hydrophobicity Value -0.059
Molecular Weight (kDa) 51.4
Isoelectric Point (pI) 5.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003347 (311 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2125

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 8 family member A1 [Source:HGNC Symbol;Acc:HGNC:15471]
E-value: 3.0e-62
Percent Identity: 32.6

References

Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes.
Boch J, Kempf B, Schmid R, Bremer E
J Bacteriol 1996 Sep;178(17):5121-9
PubMed ID: 8752328