Pseudomonas aeruginosa PAO1, PA2147 (katE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2147
Name
katE
Replicon chromosome
Genomic location 2361954 - 2364083 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq NP_250837.1
GI 15597343
Affymetrix PA2147_katE_at
Entrez 881554
GenBank AAG05535.1
INSDC AAG05535.1
NCBI Locus Tag PA2147
protein_id(GenBank) gb|AAG05535.1|AE004642_2|gnl|PseudoCAP|PA2147
TIGR NTL03PA02147
UniParc UPI00000C55D1
UniProtKB Acc Q9I1W8
UniProtKB ID CATE_PSEAE
UniRef100 UniRef100_Q9I1W8
UniRef50 UniRef50_P21179
UniRef90 UniRef90_Q9I1W8

Product

Feature Type CDS
Coding Frame 1
Product Name
catalase HPII
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -18.96
Kyte-Doolittle Hydrophobicity Value -0.401
Molecular Weight (kDa) 78.0
Isoelectric Point (pI) 5.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 322 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001474 (1465 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2147
Search term: katE
Search term: catalase HPII

Human Homologs

Ensembl 110, assembly GRCh38.p14
catalase [Source:HGNC Symbol;Acc:HGNC:1516]
E-value: 1.0e-103
Percent Identity: 40.7

References

Nucleotide sequence of Escherichia coli katE, which encodes catalase HPII.
von Ossowski I, Mulvey MR, Leco PA, Borys A, Loewen PC
J Bacteriol 1991 Jan;173(2):514-20
PubMed ID: 1987146
Crystal structure of catalase HPII from Escherichia coli.
Bravo J, Verdaguer N, Tormo J, Betzel C, Switala J, Loewen PC, Fita I
Structure 1995 May 15;3(5):491-502
PubMed ID: 7663946