Pseudomonas aeruginosa PAO1, PA2272 (pbpC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2272
Name
pbpC
Replicon chromosome
Genomic location 2501720 - 2503417 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250962.1
GI 15597468
Affymetrix PA2272_pbpC_at
Entrez 882173
GenBank AAG05660.1
INSDC AAG05660.1
NCBI Locus Tag PA2272
protein_id(GenBank) gb|AAG05660.1|AE004653_3|gnl|PseudoCAP|PA2272
TIGR NTL03PA02272
UniParc UPI00000C563C
UniProtKB Acc Q9I1K1
UniProtKB ID Q9I1K1_PSEAE
UniRef100 UniRef100_Q9I1K1
UniRef50 UniRef50_Q9I1K1
UniRef90 UniRef90_Q9I1K1

Product

Feature Type CDS
Coding Frame 1
Product Name
penicillin-binding protein 3A
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 12.86
Kyte-Doolittle Hydrophobicity Value -0.058
Molecular Weight (kDa) 61.1
Isoelectric Point (pI) 9.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 574 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003221 (300 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2272
Search term: pbpC

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Identification of a penicillin-binding protein 3 homolog, PBP3x, in Pseudomonas aeruginosa: gene cloning and growth phase-dependent expression.
Liao X, Hancock RE
J Bacteriol 1997 Mar;179(5):1490-6
PubMed ID: 9045804