Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2398
|
Name |
fpvA
|
Replicon | chromosome |
Genomic location | 2655187 - 2657634 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 4 transposon mutants in orthologs |
RefSeq | NP_251088.1 |
GI | 15597594 |
Affymetrix | PA2398_fpvA_at |
Entrez | 878605 |
GenBank | AAG05786.1 |
NCBI Locus Tag | PA2398 |
protein_id(GenBank) | gb|AAG05786.1|AE004666_2|gnl|PseudoCAP|PA2398 |
TIGR | NTL03PA02398 |
UniProtKB Acc | P48632 |
UniProtKB ID | FPVA_PSEAE |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
ferripyoverdine receptor
|
Synonyms | |
Evidence for Translation |
Verified using two-dimensional gel electrophoresis, MALDI-TOF MS and peptide mass mapping(pI:5.4, molecular weight:91.2, PMID:21674802)
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | -14.61 |
Kyte-Doolittle Hydrophobicity Value | -0.557 |
Molecular Weight (kDa) | 91.2 |
Isoelectric Point (pI) | 5.28 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2IAH | MEMBRANE PROTEIN | 09/08/06 | Crystal structure of the ferripyoverdine receptor of the outer membrane of Pseudomonas aeruginosa bound to ferripyoverdine. | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 2.73 | X-RAY DIFFRACTION | 100.0 |
1XKH | MEMBRANE PROTEIN | 09/29/04 | Pyoverdine outer membrane receptor FpvA from Pseudomonas aeruginosa PAO1 bound to pyoverdine | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 3.6 | X-RAY DIFFRACTION | 100.0 |
2W6U | MEMBRANE PROTEIN | 12/19/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(G173)-Fe complex | PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FLUORESCENS | 3 | X-RAY DIFFRACTION | 100.0 |
2W77 | RECEPTOR | 12/20/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(Pfl18.1)-Fe complex | PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FLUORESCENS | 2.9 | X-RAY DIFFRACTION | 100.0 |
2W76 | RECEPTOR | 12/20/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(Pa6)-Fe complex | PSEUDOMONAS AERUGINOSA | 2.8 | X-RAY DIFFRACTION | 100.0 |
2O5P | TRANSPORT PROTEIN | 12/06/06 | Crystal structure of the full length ferric pyoverdine outer membrane receptor FpvA of Pseudomonas aeruginosa in its apo form | Pseudomonas aeruginosa | 2.77 | X-RAY DIFFRACTION | 100.0 |
2W75 | RECEPTOR | 12/20/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: Apo-FpvA | PSEUDOMONAS AERUGINOSA | 2.9 | X-RAY DIFFRACTION | 100.0 |
5ODW | PROTEIN TRANSPORT | 07/06/17 | Structure of the FpvAI-pyocin S2 complex | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.8 | X-RAY DIFFRACTION | 100.0 |
2W16 | MEMBRANE PROTEIN | 10/14/08 | Structures of FpvA bound to heterologous pyoverdines | PSEUDOMONAS AERUGINOSA | 2.71 | X-RAY DIFFRACTION | 100.0 |
2W6T | MEMBRANE PROTEIN | 12/19/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(DSM50106)-Fe complex | PSEUDOMONAS AERUGINOSA; PSEUDOMONAS FLUORESCENS | 2.9 | X-RAY DIFFRACTION | 100.0 |
2W78 | RECEPTOR | 12/20/08 | Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: FpvA-Pvd(ATCC13535)-Fe complex | PSEUDOMONAS AERUGINOSA | 3 | X-RAY DIFFRACTION | 100.0 |
Identified by Diamond using e-value cutoff of 0.0001 and returning alignments that span 100% of the query sequence and that have more than 95% identity.
Drug Name | Source Accession | Source DB | Version | Target Accession | Target Description | Percent Identity | Alignment Length | E-Value |
3,6,9,12,15-PENTAOXATRICOSAN-1-OL | DB08249 | DrugBank | 5.1.4 | P48632 | Ferripyoverdine receptor | 100.0 | 815 | 0.0e+00 |
Source 1 | |
Database | VFDB : VF0094 |
Category | Pyoverdine receptors |
Evidence |
|
Host Organism | |
Notes | |
Reference |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 271 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG001486 (1037 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2398
Search term: fpvA
Search term: ferripyoverdine receptor
|
Cloning and nucleotide sequence analysis of the ferripyoverdine receptor gene fpvA of Pseudomonas aeruginosa.
Poole K, Neshat S, Krebes K, Heinrichs DE
J Bacteriol 1993 Aug;175(15):4597-604
PubMed ID: 8335619
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Proteomics of the oxidative stress response induced by hydrogen peroxide and paraquat reveals a novel AhpC-like protein in Pseudomonas aeruginosa.
Hare NJ, Scott NE, Shin EH, Connolly AM, Larsen MR, Palmisano G, Cordwell SJ
Proteomics 2011 Aug;11(15):3056-69
PubMed ID: 21674802
|