Pseudomonas aeruginosa PAO1, PA2815

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2815
Name
Synonym: yafH
Replicon chromosome
Genomic location 3168106 - 3170553 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251505.1
GI 15598011
Affymetrix PA2815_at
Entrez 882805
GenBank AAG06203.1
INSDC AAG06203.1
NCBI Locus Tag PA2815
protein_id(GenBank) gb|AAG06203.1|AE004708_9|gnl|PseudoCAP|PA2815
TIGR NTL03PA02815
UniParc UPI00000C5821
UniProtKB Acc Q9I028
UniProtKB ID Q9I028_PSEAE
UniRef100 UniRef100_W0YSG0
UniRef50 UniRef50_A7K0I6
UniRef90 UniRef90_V6AE19

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (88.76 kDa, PMID:21751344)
Charge (pH 7) -12.42
Kyte-Doolittle Hydrophobicity Value 0.030
Molecular Weight (kDa) 88.8
Isoelectric Point (pI) 5.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 438 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002757 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2815

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5
Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 9 [Source:HGNC Symbol;Acc:HGNC:21497]
E-value: 2.9e-33
Percent Identity: 30.5

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344