Pseudomonas aeruginosa PAO1, PA3970 (amn)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3970
Name
amn
Replicon chromosome
Genomic location 4448893 - 4450392 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252659.1
GI 15599165
Affymetrix PA3970_amn_at
Entrez 878880
GenBank AAG07357.1
INSDC AAG07357.1
NCBI Locus Tag PA3970
protein_id(GenBank) gb|AAG07357.1|AE004815_1|gnl|PseudoCAP|PA3970
TIGR NTL03PA03970
UniParc UPI00000C5BA6
UniProtKB Acc Q9HX46
UniProtKB ID Q9HX46_PSEAE
UniRef100 UniRef100_Q9HX46
UniRef50 UniRef50_Q0C2N1
UniRef90 UniRef90_Q9HX46

Product

Feature Type CDS
Coding Frame 1
Product Name
AMP nucleosidase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.26
Kyte-Doolittle Hydrophobicity Value -0.304
Molecular Weight (kDa) 56.2
Isoelectric Point (pI) 6.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 134 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001709 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3970
Search term: amn
Search term: AMP nucleosidase

Human Homologs

References

Structure and regulation of the AMP nucleosidase gene (amn) from Escherichia coli.
Leung HB, Kvalnes-Krick KL, Meyer SL, deRiel JK, Schramm VL
Biochemistry 1989 Oct 31;28(22):8726-33
PubMed ID: 2690948