Pseudomonas aeruginosa PAO1, PA4923

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4923
Name
Replicon chromosome
Genomic location 5522386 - 5522973 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Comment

Cross-References

RefSeq NP_253610.1
GI 15600116
Affymetrix PA4923_at
DNASU PaCD00008131
Entrez 879697
GenBank AAG08308.1
INSDC AAA25729.2
NCBI Locus Tag PA4923
protein_id(GenBank) gb|AAG08308.1|AE004905_6|gnl|PseudoCAP|PA4923
TIGR NTL03PA04924
UniParc UPI000013A917
UniProtKB Acc P48636
UniProtKB ID LOGH_PSEAE
UniRef100 UniRef100_P48636
UniRef50 UniRef50_P48636
UniRef90 UniRef90_P48636

Product

Feature Type CDS
Coding Frame 1
Product Name
type-I LOG protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.62
Kyte-Doolittle Hydrophobicity Value 0.210
Molecular Weight (kDa) 20.7
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5ZBJ HYDROLASE 02/12/18 Crystal structure of type-I LOG from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 1.89 X-RAY DIFFRACTION 100.0
5ZBK HYDROLASE 02/12/18 Crystal structure of type-I LOG from Pseudomonas aeruginosa PAO1 in complex with AMP Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.3 X-RAY DIFFRACTION 99.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 373 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004540 (449 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4923

Human Homologs

References

Structural insight into molecular mechanism of cytokinin activating protein from Pseudomonas aeruginosa PAO1.
Seo H, Kim KJ
Environ Microbiol 2018 Sep;20(9):3214-3223
PubMed ID: 29901273