Pseudomonas aeruginosa PAO1, PA5206 (argE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5206
Name
argE
Replicon chromosome
Genomic location 5860467 - 5861621 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253893.1
GI 15600399
Affymetrix PA5206_argE_at
DNASU PaCD00008242
Entrez 879575
GenBank AAG08591.1
INSDC AAG08591.1
NCBI Locus Tag PA5206
protein_id(GenBank) gb|AAG08591.1|AE004933_7|gnl|PseudoCAP|PA5206
TIGR NTL03PA05207
UniParc UPI00000C5F52
UniProtKB Acc Q9HTY4
UniProtKB ID Q9HTY4_PSEAE
UniRef100 UniRef100_Q9HTY4
UniRef50 UniRef50_Q9HTY4
UniRef90 UniRef90_Q9HTY4

Product

Feature Type CDS
Coding Frame 1
Product Name
acetylornithine deacetylase
Product Name Confidence: Class 2
Synonyms N-acetylornithinase
Evidence for Translation
Charge (pH 7) -9.85
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 5.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 464 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004790 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5206
Search term: argE

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Structural and biochemical characterization of the Escherichia coli argE gene product.
Meinnel T, Schmitt E, Mechulam Y, Blanquet S
J Bacteriol 1992 Apr;174(7):2323-31
PubMed ID: 1551850