Pseudomonas aeruginosa PAO1, PA5223 (ubiH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5223
Name
ubiH
Synonym: visB
Replicon chromosome
Genomic location 5880487 - 5881671 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253910.1
GI 15600416
Affymetrix PA5223_ubiH_at
Entrez 882287
GenBank AAG08608.1
INSDC AAG08608.1
NCBI Locus Tag PA5223
protein_id(GenBank) gb|AAG08608.1|AE004935_5|gnl|PseudoCAP|PA5223
TIGR NTL03PA05224
UniParc UPI00000C5F61
UniProtKB Acc Q9HTW7
UniProtKB ID Q9HTW7_PSEAE
UniRef100 UniRef100_W0YYZ6
UniRef50 UniRef50_A6VDZ7
UniRef90 UniRef90_A6VDZ7

Product

Feature Type CDS
Coding Frame 1
Product Name
ubiH protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.74
Kyte-Doolittle Hydrophobicity Value -0.060
Molecular Weight (kDa) 43.0
Isoelectric Point (pI) 6.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 249 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004804 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5223
Search term: ubiH
Search term: ubiH protein

Human Homologs

Ensembl 110, assembly GRCh38.p14
coenzyme Q6, monooxygenase [Source:HGNC Symbol;Acc:HGNC:20233]
E-value: 2.0e-32
Percent Identity: 27.8

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone.
Nakahigashi K, Miyamoto K, Nishimura K, Inokuchi H
J Bacteriol 1992 Nov;174(22):7352-9
PubMed ID: 1339425