Pseudomonas aeruginosa PAO1, PA1068
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA1068
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 1153637 - 1155547 (+ strand) |
| Transposon Mutants | 3 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_249759.1 |
| GI | 15596265 |
| Affymetrix | PA1068_at |
| Entrez | 879652 |
| GenBank | AAG04457.1 |
| INSDC | AAG04457.1 |
| NCBI Locus Tag | PA1068 |
| protein_id(GenBank) | gb|AAG04457.1|AE004538_9|gnl|PseudoCAP|PA1068 |
| TIGR | NTL03PA01069 |
| UniParc | UPI00000C5236 |
| UniProtKB Acc | Q9I4Q6 |
| UniProtKB ID | Q9I4Q6_PSEAE |
| UniRef100 | UniRef100_Q9I4Q6 |
| UniRef50 | UniRef50_B7LVF2 |
| UniRef90 | UniRef90_A0A038C8K8 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
probable heat shock protein (hsp90 family)
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | -12.28 |
| Kyte-Doolittle Hydrophobicity Value | -0.289 |
| Molecular Weight (kDa) | 70.7 |
| Isoelectric Point (pI) | 5.65 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001030 (301 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA1068
Search term: probable heat shock protein (hsp90 family)
|
Human Homologs
|
Ensembl
107, assembly
GRCh38.p13
|
TNF receptor associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16264]
E-value:
3.1e-27
Percent Identity:
24.4
|
|
Ensembl
107, assembly
GRCh38.p13
|
TNF receptor associated protein 1 [Source:HGNC Symbol;Acc:HGNC:16264]
E-value:
3.1e-27
Percent Identity:
24.4
|
References
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
|
Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases.
Nadeau K, Das A, Walsh CT
J. Biol. Chem. 1993 Jan;268(2):1479-87
PubMed ID: 8419347
|