Pseudomonas aeruginosa PAO1, PA1078 (flgC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1078
Name
flgC
Replicon chromosome
Genomic location 1164688 - 1165128 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249769.1
GI 15596275
Affymetrix PA1078_flgC_at
Entrez 879618
GenBank AAG04467.1
INSDC AAG04467.1
NCBI Locus Tag PA1078
protein_id(GenBank) gb|AAG04467.1|AE004539_9|gnl|PseudoCAP|PA1078
TIGR NTL03PA01079
UniParc UPI00000C523B
UniProtKB Acc Q9I4Q1
UniProtKB ID Q9I4Q1_PSEAE
UniRef100 UniRef100_W0YM06
UniRef50 UniRef50_P0A1I8
UniRef90 UniRef90_W0YM06

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar basal-body rod protein FlgC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.53
Kyte-Doolittle Hydrophobicity Value -0.227
Molecular Weight (kDa) 15.6
Isoelectric Point (pI) 4.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 317 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001040 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1078
Search term: flgC

Human Homologs

References

FlgB, FlgC, FlgF and FlgG. A family of structurally related proteins in the flagellar basal body of Salmonella typhimurium.
Homma M, Kutsukake K, Hasebe M, Iino T, Macnab RM
J Mol Biol 1990 Jan 20;211(2):465-77
PubMed ID: 2129540
Stoichiometric analysis of the flagellar hook-(basal-body) complex of Salmonella typhimurium.
Jones CJ, Macnab RM, Okino H, Aizawa S
J Mol Biol 1990 Mar 20;212(2):377-87
PubMed ID: 2181149