Pseudomonas aeruginosa PAO1, PA1976 (ercS')

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1976
Name
ercS'
Replicon chromosome
Genomic location 2160363 - 2163008 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250666.1
GI 15597172
Affymetrix PA1976_at
Entrez 880111
GenBank AAG05364.1
INSDC AAG05364.1
NCBI Locus Tag PA1976
protein_id(GenBank) gb|AAG05364.1|AE004624_3|gnl|PseudoCAP|PA1976
TIGR NTL03PA01976
UniParc UPI00000C553C
UniProtKB Acc Q9I2C9
UniProtKB ID Q9I2C9_PSEAE
UniRef100 UniRef100_Q9I2C9
UniRef50 UniRef50_Q9I2C9
UniRef90 UniRef90_Q9I2C9

Product

Feature Type CDS
Coding Frame 1
Product Name
ErcS'
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.28
Kyte-Doolittle Hydrophobicity Value -0.344
Molecular Weight (kDa) 99.0
Isoelectric Point (pI) 7.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 615 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003457 (422 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1976
Search term: ercS'
Search term: ErcS'

Human Homologs

References

A complex regulatory network controls aerobic ethanol oxidation in Pseudomonas aeruginosa: indication of four levels of sensor kinases and response regulators.
Mern DS, Ha SW, Khodaverdi V, Gliese N, Görisch H
Microbiology (Reading) 2010 May;156(Pt 5):1505-1516
PubMed ID: 20093290