Pseudomonas aeruginosa PAO1, PA2079

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2079
Name
Replicon chromosome
Genomic location 2287523 - 2288929 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_250769.1
GI 15597275
Affymetrix PA2079_at
Entrez 878467
GenBank AAG05467.1
INSDC AAG05467.1
NCBI Locus Tag PA2079
protein_id(GenBank) gb|AAG05467.1|AE004635_5|gnl|PseudoCAP|PA2079
TIGR NTL03PA02079
UniParc UPI00000C558E
UniProtKB Acc Q9I236
UniProtKB ID Q9I236_PSEAE
UniRef100 UniRef100_A0A0A8RRC1
UniRef50 UniRef50_W0WHZ7
UniRef90 UniRef90_W0WHZ7

Product

Feature Type CDS
Coding Frame 1
Product Name
probable amino acid permease
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.26
Kyte-Doolittle Hydrophobicity Value 0.793
Molecular Weight (kDa) 50.5
Isoelectric Point (pI) 9.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 358 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000219 (3043 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2079

Human Homologs

Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 4 [Source:HGNC Symbol;Acc:HGNC:11062]
E-value: 1.1e-11
Percent Identity: 25.9
Ensembl 110, assembly GRCh38.p14
novel protein
E-value: 1.1e-11
Percent Identity: 25.9
Ensembl 110, assembly GRCh38.p14
solute carrier family 7 member 4 [Source:HGNC Symbol;Acc:HGNC:11062]
E-value: 1.1e-11
Percent Identity: 25.9

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295