Pseudomonas aeruginosa PAO1, PA2142

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2142
Name
Synonym: yhxC
Replicon chromosome
Genomic location 2356713 - 2357573 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250832.1
GI 15597338
Affymetrix PA2142_at
DNASU PaCD00006946
Entrez 881828
GenBank AAG05530.1
INSDC AAG05530.1
NCBI Locus Tag PA2142
protein_id(GenBank) gb|AAG05530.1|AE004641_9|gnl|PseudoCAP|PA2142
TIGR NTL03PA02142
UniParc UPI00000C55CC
UniProtKB Acc Q9I1X3
UniProtKB ID Q9I1X3_PSEAE
UniRef100 UniRef100_Q9I1X3
UniRef50 UniRef50_P80873
UniRef90 UniRef90_A0A0A8RS25

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.89
Kyte-Doolittle Hydrophobicity Value -0.279
Molecular Weight (kDa) 30.9
Isoelectric Point (pI) 6.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003332 (498 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2142

Human Homologs

Ensembl 110, assembly GRCh38.p14
3-hydroxybutyrate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:32389]
E-value: 9.3e-27
Percent Identity: 34.3

References

No references are associated with this feature.