Pseudomonas aeruginosa PAO1, PA2181

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2181
Name
Replicon chromosome
Genomic location 2403151 - 2404284 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250871.1
GI 15597377
Affymetrix PA2181_at
DNASU PaCD00006965
Entrez 877967
GenBank AAG05569.1
INSDC AAG05569.1
NCBI Locus Tag PA2181
protein_id(GenBank) gb|AAG05569.1|AE004645_3|gnl|PseudoCAP|PA2181
TIGR NTL03PA02181
UniParc UPI00000C55F1
UniProtKB Acc Q9I1T4
UniProtKB ID GCS2_PSEAE
UniRef100 UniRef100_Q9I1T4
UniRef50 UniRef50_Q9I1T4
UniRef90 UniRef90_Q9I1T4

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 2.75
Kyte-Doolittle Hydrophobicity Value -0.226
Molecular Weight (kDa) 42.4
Isoelectric Point (pI) 7.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 182 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003292 (377 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2181

Human Homologs

References

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae.
Philipp WJ, Poulet S, Eiglmeier K, Pascopella L, Balasubramanian V, Heym B, Bergh S, Bloom BR, Jacobs WR Jr, Cole ST
Proc Natl Acad Sci U S A 1996 Apr 2;93(7):3132-7
PubMed ID: 8610181