Pseudomonas aeruginosa PAO1, PA2239 (pslI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2239
Name
pslI
Replicon chromosome
Genomic location 2463996 - 2465099 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs
Commentpsl cluster plays a role in cell-cell and/or cell-surface interaction in biofilm formation.

Cross-References

RefSeq NP_250929.1
GI 15597435
Affymetrix PA2239_at
Entrez 882276
GenBank AAG05627.1
INSDC AAG05627.1
NCBI Locus Tag PA2239
protein_id(GenBank) gb|AAG05627.1|AE004649_18|gnl|PseudoCAP|PA2239
TIGR NTL03PA02239
UniParc UPI00000C5625
UniProtKB Acc Q9I1N0
UniProtKB ID Q9I1N0_PSEAE
UniRef100 UniRef100_Q9I1N0
UniRef50 UniRef50_Q4K8X6
UniRef90 UniRef90_B7V984

Product

Feature Type CDS
Coding Frame 1
Product Name
PslI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.87
Kyte-Doolittle Hydrophobicity Value -0.172
Molecular Weight (kDa) 40.6
Isoelectric Point (pI) 8.61

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 275 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001311 (2094 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2239
Search term: pslI
Search term: PslI

Human Homologs

References

Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production.
Byrd MS, Sadovskaya I, Vinogradov E, Lu H, Sprinkle AB, Richardson SH, Ma L, Ralston B, Parsek MR, Anderson EM, Lam JS, Wozniak DJ
Mol Microbiol 2009 Aug;73(4):622-38
PubMed ID: 19659934