Pseudomonas aeruginosa PAO1, PA2338

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2338
Name
Synonym: mtlE
Replicon chromosome
Genomic location 2582097 - 2583407 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251028.1
GI 15597534
Affymetrix PA2338_at
Entrez 883086
GenBank AAG05726.1
INSDC AAG05726.1
NCBI Locus Tag PA2338
protein_id(GenBank) gb|AAG05726.1|AE004660_2|gnl|PseudoCAP|PA2338
TIGR NTL03PA02338
UniParc UPI00000C5678
UniProtKB Acc Q9I1E0
UniProtKB ID Q9I1E0_PSEAE
UniRef100 UniRef100_W0YU12
UniRef50 UniRef50_G0AJ01
UniRef90 UniRef90_A0A077K0W6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable binding protein component of ABC maltose/mannitol transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.36
Kyte-Doolittle Hydrophobicity Value -0.144
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 7.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 234 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003176 (440 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2338

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Structure and function of the genes involved in mannitol, arabitol and glucitol utilization from Pseudomonas fluorescens DSM50106.
Brünker P, Altenbuchner J, Mattes R
Gene 1998 Jan 5;206(1):117-26
PubMed ID: 9461423