Pseudomonas aeruginosa PAO1, PA2344 (mtlZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2344
Name
mtlZ
Synonym: frk
Replicon chromosome
Genomic location 2589455 - 2590387 (+ strand)
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251034.1
GI 15597540
Affymetrix PA2344_mtlZ_at
DNASU PaCD00007026
Entrez 878614
GenBank AAG05732.1
INSDC AAG05732.1
NCBI Locus Tag PA2344
protein_id(GenBank) gb|AAG05732.1|AE004660_8|gnl|PseudoCAP|PA2344
TIGR NTL03PA02344
UniParc UPI00000C567E
UniProtKB Acc Q9I1D4
UniProtKB ID Q9I1D4_PSEAE
UniRef100 UniRef100_W0YQX2
UniRef50 UniRef50_Q4KC51
UniRef90 UniRef90_B7V8X8

Product

Feature Type CDS
Coding Frame 1
Product Name
fructokinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.25
Kyte-Doolittle Hydrophobicity Value 0.071
Molecular Weight (kDa) 33.1
Isoelectric Point (pI) 6.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 333 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003171 (910 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2344
Search term: mtlZ
Search term: fructokinase

Human Homologs

References

Structure and function of the genes involved in mannitol, arabitol and glucitol utilization from Pseudomonas fluorescens DSM50106.
Brünker P, Altenbuchner J, Mattes R
Gene 1998 Jan 5;206(1):117-26
PubMed ID: 9461423