Pseudomonas aeruginosa PAO1, PA2462

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA2462
Name
Replicon chromosome
Genomic location 2761921 - 2778804 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_251152.1
GI 15597658
Affymetrix PA2462_at
Entrez 882914
GenBank AAG05850.1
INSDC AAG05850.1
NCBI Locus Tag PA2462
protein_id(GenBank) gb|AAG05850.1|AE004673_10|gnl|PseudoCAP|PA2462
TIGR NTL03PA02462
UniParc UPI0000110219
UniProtKB Acc Q9I120
UniProtKB ID Q9I120_PSEAE
UniRef100 UniRef100_Q9I120
UniRef50 UniRef50_X7DPP0
UniRef90 UniRef90_X7DPP0

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (573.17 kDa, PMID:21751344)
Charge (pH 7) -70.71
Kyte-Doolittle Hydrophobicity Value -0.151
Molecular Weight (kDa) 573.2
Isoelectric Point (pI) 5.13

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Outer Membrane Class 2
Outer Membrane Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category Not available / Not known
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Hordeum vulgare
Notes
Infection model Barley seed pathogenicity assay
Reference 21261818

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 78 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000041 (624 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2462

Human Homologs

References

Filamentous hemagglutinin of Bordetella pertussis: nucleotide sequence and crucial role in adherence.
Relman DA, Domenighini M, Tuomanen E, Rappuoli R, Falkow S
Proc Natl Acad Sci U S A 1989 Apr;86(8):2637-41
PubMed ID: 2539596
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344