Pseudomonas aeruginosa PAO1, PA2500

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2500
Name
Synonym: cynX
Replicon chromosome
Genomic location 2817449 - 2818675 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_251190.1
GI 15597696
Affymetrix PA2500_at
Entrez 882882
GenBank AAG05888.1
INSDC AAG05888.1
NCBI Locus Tag PA2500
protein_id(GenBank) gb|AAG05888.1|AE004677_5|gnl|PseudoCAP|PA2500
TIGR NTL03PA02500
UniParc UPI00000C570A
UniProtKB Acc Q9I0Y2
UniProtKB ID Q9I0Y2_PSEAE
UniRef100 UniRef100_U9J025
UniRef50 UniRef50_A0A024HH26
UniRef90 UniRef90_W0WH22

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 11.24
Kyte-Doolittle Hydrophobicity Value 0.818
Molecular Weight (kDa) 43.1
Isoelectric Point (pI) 9.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 180 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000270 (1361 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2500

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization of the cyn operon in Escherichia coli K12.
Sung YC, Fuchs JA
J Biol Chem 1988 Oct 15;263(29):14769-75
PubMed ID: 3049588