Pseudomonas aeruginosa PAO1, PA2743 (infC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2743
Name
infC
Replicon chromosome
Genomic location 3104279 - 3104830 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_251433.1
GI 15597939
Affymetrix PA2743_infC_at
DNASU PaCD00007188
Entrez 879427
GenBank AAG06131.1
INSDC AAG06131.1
NCBI Locus Tag PA2743
protein_id(GenBank) gb|AAG06131.1|AE004702_8|gnl|PseudoCAP|PA2743
TIGR NTL03PA02743
UniParc UPI000012D342
UniProtKB Acc Q9I0A0
UniProtKB ID IF3_PSEAE
UniRef100 UniRef100_Q9I0A0
UniRef50 UniRef50_Q4KEW3
UniRef90 UniRef90_Q9I0A0

Product

Feature Type CDS
Coding Frame 1
Product Name
translation initiation factor IF-3
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
Charge (pH 7) 9.69
Kyte-Doolittle Hydrophobicity Value -0.608
Molecular Weight (kDa) 20.9
Isoelectric Point (pI) 10.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6VRJ TRANSLATION 02/07/20 Solution structure of Pseudomonas aeruginosa IF3 C-terminal domain Pseudomonas aeruginosa NOT SOLUTION NMR 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 582 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002828 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2743
Search term: infC

Human Homologs

References

Physiological effects of translation initiation factor IF3 and ribosomal protein L20 limitation in Escherichia coli.
Olsson CL, Graffe M, Springer M, Hershey JW
Mol Gen Genet 1996 Apr 10;250(6):705-14
PubMed ID: 8628231
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142