Pseudomonas aeruginosa PAO1, PA3103 (xcpR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3103
Name
xcpR
Replicon chromosome
Genomic location 3481914 - 3483422 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_251793.1
GI 15598299
Affymetrix PA3103_xcpR_at
Entrez 877804
GenBank AAG06491.1
INSDC AAG06491.1
NCBI Locus Tag PA3103
protein_id(GenBank) gb|AAG06491.1|AE004734_9|gnl|PseudoCAP|PA3103
TIGR NTL03PA03103
UniParc UPI000012BC32
UniProtKB Acc Q00512
UniProtKB ID GSPE_PSEAE
UniRef100 UniRef100_Q00512
UniRef50 UniRef50_Q00512
UniRef90 UniRef90_Q00512

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretion pathway protein E
Product Name Confidence: Class 1
Synonyms type II traffic warden ATPase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.05
Kyte-Doolittle Hydrophobicity Value -0.196
Molecular Weight (kDa) 55.5
Isoelectric Point (pI) 6.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 503 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000665 (786 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3103
Search term: xcpR

Human Homologs

References

Subcomplexes from the Xcp secretion system of Pseudomonas aeruginosa.
Robert V, Filloux A, Michel GP
FEMS Microbiol Lett 2005 Nov 1;252(1):43-50
PubMed ID: 16168578
Protein secretion in Pseudomonas aeruginosa: characterization of seven xcp genes and processing of secretory apparatus components by prepilin peptidase.
Bally M, Filloux A, Akrim M, Ball G, Lazdunski A, Tommassen J
Mol Microbiol 1992 May;6(9):1121-31
PubMed ID: 1588814