Pseudomonas aeruginosa PAO1, PA3187

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3187
Name
Synonym: gltK
Replicon chromosome
Genomic location 3577320 - 3578480 (- strand)
Transposon Mutants 4 transposon mutants in PAO1

Cross-References

RefSeq NP_251877.1
GI 15598383
Affymetrix PA3187_at
DNASU PaCD00007404
Entrez 880539
GenBank AAG06575.1
INSDC AAG06575.1
NCBI Locus Tag PA3187
protein_id(GenBank) gb|AAG06575.1|AE004742_11|gnl|PseudoCAP|PA3187
TIGR NTL03PA03187
UniParc UPI00000C593E
UniProtKB Acc Q9HZ51
UniProtKB ID Q9HZ51_PSEAE
UniRef100 UniRef100_Z2DHW7
UniRef50 UniRef50_G8PWC9
UniRef90 UniRef90_V6ABT9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable ATP-binding component of ABC transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Detected using LC-MS/MS (42.24 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.09
Kyte-Doolittle Hydrophobicity Value -0.136
Molecular Weight (kDa) 42.2
Isoelectric Point (pI) 7.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002429 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3187

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3
Ensembl 110, assembly GRCh38.p14
ATP binding cassette subfamily G member 1 [Source:HGNC Symbol;Acc:HGNC:73]
E-value: 9.3e-14
Percent Identity: 29.3

References

Nucleotide sequence of the ugp genes of Escherichia coli K-12: homology to the maltose system.
Overduin P, Boos W, Tommassen J
Mol Microbiol 1988 Nov;2(6):767-75
PubMed ID: 3062310
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344