Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA3227
|
Name |
ppiA
Synonym: cypH |
Replicon | chromosome |
Genomic location | 3614304 - 3614867 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_251917.1 |
GI | 15598423 |
Affymetrix | PA3227_ppiA_at |
DNASU | PaCD00007420 |
Entrez | 882464 |
GenBank | AAG06615.1 |
INSDC | CAA58868.1 |
NCBI Locus Tag | PA3227 |
protein_id(GenBank) | gb|AAG06615.1|AE004745_12|gnl|PseudoCAP|PA3227 |
TIGR | NTL03PA03227 |
UniParc | UPI000013206E |
UniProtKB Acc | Q59641 |
UniProtKB ID | PPIA_PSEAE |
UniRef100 | UniRef100_Q59641 |
UniRef50 | UniRef50_O53021 |
UniRef90 | UniRef90_Q59641 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
peptidyl-prolyl cis-trans isomerase A
|
Synonyms |
Rotamase A, PPIase A Cyclophilin A |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Detected by two-dimensional gel electrophoresis and mass spectral analysis(PMID:21863142).
|
Charge (pH 7) | 1.68 |
Kyte-Doolittle Hydrophobicity Value | 0.119 |
Molecular Weight (kDa) | 20.1 |
Isoelectric Point (pI) | 8.46 |
Individual Mappings | |
Additional evidence for subcellular localization |
Detetected in a periplasmic protein preparation by spheroplasting by lysozyme and MgCl2.(PMID:19333994)
|
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 553 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002387 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA3227
Search term: ppiA
Search term: peptidyl-prolyl cis-trans isomerase A
|
Ensembl
110, assembly
GRCh38.p14
|
peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]
E-value:
1.3e-16
Percent Identity:
36.8
|
Ensembl
110, assembly
GRCh38.p14
|
peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]
E-value:
1.3e-16
Percent Identity:
36.8
|
Ensembl
110, assembly
GRCh38.p14
|
peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:28954]
E-value:
1.3e-16
Percent Identity:
36.8
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Two distinct forms of peptidylprolyl-cis-trans-isomerase are expressed separately in periplasmic and cytoplasmic compartments of Escherichia coli cells.
Hayano T, Takahashi N, Kato S, Maki N, Suzuki M
Biochemistry 1991 Mar 26;30(12):3041-8
PubMed ID: 2007139
|
Three-dimensional solution structure of Escherichia coli periplasmic cyclophilin.
Clubb RT, Ferguson SB, Walsh CT, Wagner G
Biochemistry 1994 Mar 15;33(10):2761-72
PubMed ID: 8130188
|
Physical mapping of 32 genetic markers on the Pseudomonas aeruginosa PAO1 chromosome.
Liao X, Charlebois I, Ouellet C, Morency MJ, Dewar K, Lightfoot J, Foster J, Siehnel R, Schweizer H, Lam JS, Hancock REW, Levesque RC
Microbiology (Reading) 1996 Jan;142 ( Pt 1):79-86
PubMed ID: 8581173
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142
|