Pseudomonas aeruginosa PAO1, PA3467

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3467
Name
Replicon chromosome
Genomic location 3879559 - 3880926 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252157.1
GI 15598663
Affymetrix PA3467_at
Entrez 877977
GenBank AAG06855.1
INSDC AAG06855.1
NCBI Locus Tag PA3467
protein_id(GenBank) gb|AAG06855.1|AE004767_6|gnl|PseudoCAP|PA3467
TIGR NTL03PA03467
UniParc UPI00000C5A29
UniProtKB Acc Q9HYD9
UniProtKB ID Q9HYD9_PSEAE
UniRef100 UniRef100_S0J3Y3
UniRef50 UniRef50_A1WJL6
UniRef90 UniRef90_A6V1V9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 6.08
Kyte-Doolittle Hydrophobicity Value 0.632
Molecular Weight (kDa) 49.4
Isoelectric Point (pI) 9.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 516 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001513 (768 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3467

Human Homologs

Ensembl 110, assembly GRCh38.p14
SVOP like [Source:HGNC Symbol;Acc:HGNC:27034]
E-value: 1.1e-26
Percent Identity: 25.3
Ensembl 110, assembly GRCh38.p14
SVOP like [Source:HGNC Symbol;Acc:HGNC:27034]
E-value: 1.1e-26
Percent Identity: 25.3

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295