Pseudomonas aeruginosa PAO1, PA4864 (ureD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4864
Name
ureD
Replicon chromosome
Genomic location 5462763 - 5463605 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_253551.1
GI 15600057
Affymetrix PA4864_ureD_at
Entrez 879776
GenBank AAG08249.1
INSDC AAG08249.1
NCBI Locus Tag PA4864
protein_id(GenBank) gb|AAG08249.1|AE004900_3|gnl|PseudoCAP|PA4864
TIGR NTL03PA04865
UniParc UPI00000C5E46
UniProtKB Acc Q9HUU9
UniProtKB ID URED_PSEAE
UniRef100 UniRef100_Q9HUU9
UniRef50 UniRef50_Q9HUU9
UniRef90 UniRef90_Q9HUU9

Product

Feature Type CDS
Coding Frame 1
Product Name
urease accessory protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 2.49
Kyte-Doolittle Hydrophobicity Value -0.108
Molecular Weight (kDa) 30.8
Isoelectric Point (pI) 7.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 186 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004492 (519 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4864
Search term: ureD

Human Homologs

References

Klebsiella aerogenes urease gene cluster: sequence of ureD and demonstration that four accessory genes (ureD, ureE, ureF, and ureG) are involved in nickel metallocenter biosynthesis.
Lee MH, Mulrooney SB, Renner MJ, Markowicz Y, Hausinger RP
J Bacteriol 1992 Jul;174(13):4324-30
PubMed ID: 1624427