Pseudomonas aeruginosa PAO1, PA4952

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4952
Name
Synonym: yjeQ
Replicon chromosome
Genomic location 5556935 - 5557954 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253639.1
GI 15600145
Affymetrix PA4952_at
Entrez 878216
GenBank AAG08337.1
INSDC AAG08337.1
NCBI Locus Tag PA4952
protein_id(GenBank) gb|AAG08337.1|AE004908_3|gnl|PseudoCAP|PA4952
TIGR NTL03PA04953
UniParc UPI00000C5E8F
UniProtKB Acc Q9HUL3
UniProtKB ID RSGA_PSEAE
UniRef100 UniRef100_Q9HUL3
UniRef50 UniRef50_Q4KJ82
UniRef90 UniRef90_Q9HUL3

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.25
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 37.1
Isoelectric Point (pI) 6.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6H4D RNA BINDING PROTEIN 07/20/18 Crystal structure of RsgA from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1 2.9 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 465 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004567 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4952

Human Homologs

References

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM
Science 1995 Jul 28;269(5223):496-512
PubMed ID: 7542800
A genome-based approach for the identification of essential bacterial genes.
Arigoni F, Talabot F, Peitsch M, Edgerton MD, Meldrum E, Allet E, Fish R, Jamotte T, Curchod ML, Loferer H
Nat Biotechnol 1998 Sep;16(9):851-6
PubMed ID: 9743119