Pseudomonas syringae pv. syringae B728a, Psyr_1743

Gene Feature Overview

Strain	Pseudomonas syringae pv. syringae B728a (Feil et al., 2005) GCF_000012245.1|latest
Locus Tag	Psyr_1743
Name
Replicon	chromosome
Genomic location	1980210 - 1981064 (- strand)

Cross-References

RefSeq	YP_234829.1
GI	66044988
EC Number	1.5.1.5
Entrez	3367248
INSDC	AAY36791.1
NCBI Locus Tag	Psyr_1743
UniParc	UPI0000394E11
UniProtKB Acc	Q4ZVN1
UniProtKB ID	FOLD1_PSEU2
UniRef100	UniRef100_Q4ZVN1
UniRef50	UniRef50_Q4K9J4
UniRef90	UniRef90_Q4K9J4

Product

Feature Type	CDS
Coding Frame	1
Product Name	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase
Synonyms
Evidence for Translation
Charge (pH 7)	-2.68
Kyte-Doolittle Hydrophobicity Value	0.113
Molecular Weight (kDa)	30.3
Isoelectric Point (pI)	6.25

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 620 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG003602 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Psyr_1743 Search term: bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000379108 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865] E-value: 1.3e-57 Percent Identity: 43.4
Ensembl 110, assembly GRCh38.p14	ENSP00000321984 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [Source:HGNC Symbol;Acc:HGNC:31865] E-value: 1.3e-57 Percent Identity: 43.4
Ensembl 110, assembly GRCh38.p14	ENSP00000498511 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000477199 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000513155 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000513157 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000513156 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000438588 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000513158 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5
Ensembl 110, assembly GRCh38.p14	ENSP00000498336 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 [Source:HGNC Symbol;Acc:HGNC:7432] E-value: 1.3e-57 Percent Identity: 44.5

References