Pseudomonas aeruginosa UCBPP-PA14, PA14_24060 (xcpW)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_24060
Name
xcpW
Replicon chromosome
Genomic location 2088952 - 2089665 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq YP_790075.1
GI 116051094
Entrez 4381098
INSDC ABJ12330.1
NCBI Locus Tag PA14_24060
UniParc UPI000012BC5A
UniProtKB Acc Q02PR1
UniProtKB ID Q02PR1_PSEAB
UniRef100 UniRef100_Q00517
UniRef50 UniRef50_Q00517
UniRef90 UniRef90_Q00517

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretion pathway protein J
Synonyms
Evidence for Translation
Charge (pH 7) -6.03
Kyte-Doolittle Hydrophobicity Value -0.685
Molecular Weight (kDa) 27.1
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6UTU PROTEIN TRANSPORT 10/30/19 Crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa in the P3 space group Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.85 X-RAY DIFFRACTION 100.0
5VTM TRANSPORT PROTEIN 05/17/17 The crystal structure of minor pseudopilin ternary complex of XcpVWX from the Type 2 secretion system of Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.041 X-RAY DIFFRACTION 100.0
5BW0 PROTEIN TRANSPORT 06/05/15 The crystal structure of minor pseudopilin binary complex of XcpV and XcpW from the Type 2 secretion system of Pseudomonas aeruginosa Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 100.0
3NJE PROTEIN TRANSPORT 06/17/10 Structure of the Minor Pseudopilin XcpW from the Pseudomonas aeruginosa Type II Secretion System Pseudomonas aeruginosa 1.85 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 72 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000656 (743 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_24060
Search term: xcpW

Human Homologs

References

No references are associated with this feature.