Pseudomonas aeruginosa UCBPP-PA14, PA14_38480 (gnyA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_38480
Name
gnyA
Replicon chromosome
Genomic location 3431547 - 3433514 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_791227.1
GI 116049963
Entrez 4380297
INSDC ABJ11199.1
NCBI Locus Tag PA14_38480
UniParc UPI000045D24A
UniProtKB Acc Q02LF9
UniProtKB ID Q02LF9_PSEAB
UniRef100 UniRef100_Q02LF9
UniRef50 UniRef50_Q9I299
UniRef90 UniRef90_Q9I299

Product

Feature Type CDS
Coding Frame 1
Product Name
alpha subunit of geranoyl-CoA carboxylase, GnyA
Synonyms
Evidence for Translation
Charge (pH 7) -16.10
Kyte-Doolittle Hydrophobicity Value -0.223
Molecular Weight (kDa) 71.1
Isoelectric Point (pI) 5.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3U9S LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex Pseudomonas aeruginosa 3.5 X-RAY DIFFRACTION 98.6
3U9T LIGASE 10/19/11 Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme Pseudomonas aeruginosa 2.9 X-RAY DIFFRACTION 98.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003427 (523 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_38480
Search term: gnyA

Human Homologs

Ensembl 110, assembly GRCh38.p14
methylcrotonyl-CoA carboxylase subunit 1 [Source:HGNC Symbol;Acc:HGNC:6936]
E-value: 5.4e-163
Percent Identity: 45.9

References

No references are associated with this feature.