Pseudomonas aeruginosa UCBPP-PA14, PA14_51390 (pqsD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51390
Name
pqsD
Replicon chromosome
Genomic location 4566976 - 4567989 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 6 transposon mutants in orthologs

Cross-References

RefSeq YP_792272.1
GI 116048927
EC Number 2.3.1.41
Entrez 4379983
INSDC ABJ10163.1
NCBI Locus Tag PA14_51390
UniParc UPI0000396584
UniProtKB Acc Q02IG4
UniProtKB ID Q02IG4_PSEAB
UniRef100 UniRef100_Q02IG4
UniRef50 UniRef50_P20582
UniRef90 UniRef90_P20582

Product

Feature Type CDS
Coding Frame 1
Product Name
3-oxoacyl-ACP synthase
Synonyms
Evidence for Translation
Charge (pH 7) -9.53
Kyte-Doolittle Hydrophobicity Value 0.079
Molecular Weight (kDa) 36.4
Isoelectric Point (pI) 5.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3H76 TRANSFERASE 04/24/09 Crystal structure of PqsD, a key enzyme in Pseudomonas aeruginosa quinolone signal biosynthesis pathway Pseudomonas aeruginosa PAO1 1.8 X-RAY DIFFRACTION 99.7
3H78 TRANSFERASE 04/24/09 Crystal structure of Pseudomonas aeruginosa PqsD C112A mutant in complex with anthranilic acid Pseudomonas aeruginosa PAO1 1.7 X-RAY DIFFRACTION 99.4
3H77 TRANSFERASE 04/24/09 Crystal structure of Pseudomonas aeruginosa PqsD in a covalent complex with anthranilate Pseudomonas aeruginosa PAO1 1.8 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000962 (605 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51390
Search term: pqsD

Human Homologs

References

No references are associated with this feature.