Pseudomonas aeruginosa UCBPP-PA14, PA14_52040 (purM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_52040
Name
purM
Replicon chromosome
Genomic location 4617733 - 4618794 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_792330.1
GI 116048869
EC Number 6.3.3.1
Entrez 4380022
INSDC ABJ10105.1
NCBI Locus Tag PA14_52040
UniParc UPI000045D078
UniProtKB Acc Q02IA6
UniProtKB ID PUR5_PSEAB
UniRef100 UniRef100_B7UXY9
UniRef50 UniRef50_Q8XAC5
UniRef90 UniRef90_Q9I513

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphoribosylaminoimidazole synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -15.06
Kyte-Doolittle Hydrophobicity Value 0.105
Molecular Weight (kDa) 37.2
Isoelectric Point (pI) 4.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 607 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000911 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_52040
Search term: purM

Human Homologs

Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 1.4e-93
Percent Identity: 50.1
Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 1.4e-93
Percent Identity: 50.1
Ensembl 110, assembly GRCh38.p14
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [Source:HGNC Symbol;Acc:HGNC:4163]
E-value: 1.4e-93
Percent Identity: 50.1

References

No references are associated with this feature.