Pseudomonas aeruginosa UCBPP-PA14, PA14_61860

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_61860
Name
Replicon chromosome
Genomic location 5517418 - 5518065 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq YP_793138.1
GI 116052821
Entrez 4385674
INSDC ABJ14057.1
NCBI Locus Tag PA14_61860
UniParc UPI00000C5DBC
UniProtKB Acc Q02FZ8
UniProtKB ID Q02FZ8_PSEAB
UniRef100 UniRef100_W0Z3D7
UniRef50 UniRef50_W0Z3D7
UniRef90 UniRef90_W0Z3D7

Product

Feature Type CDS
Coding Frame 1
Product Name
carbonic anhydrase
Synonyms
Evidence for Translation
Charge (pH 7) -5.06
Kyte-Doolittle Hydrophobicity Value -0.149
Molecular Weight (kDa) 24.2
Isoelectric Point (pI) 6.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6D2N LYASE 04/13/18 Beta Carbonic anhydrase in complex with a sulfonamide anion Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 100.0
5BQ1 LYASE 05/28/15 Capturing Carbon Dioxide in beta Carbonic Anhydrase Pseudomonas aeruginosa 1.6 X-RAY DIFFRACTION 100.0
4RXY LYASE 12/12/14 Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.901 X-RAY DIFFRACTION 100.0
6D2O LYASE 04/13/18 Beta Carbonic anhydrase in complex with 4-methylimidazole Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 100.0
6D2M LYASE 04/13/18 Beta Carbonic anhydrase in complex with thiocyanate Pseudomonas aeruginosa 1.9 X-RAY DIFFRACTION 100.0
6D2J LYASE 04/13/18 Beta Carbonic anhydrase in complex with thiocyanate Pseudomonas aeruginosa 2.1 X-RAY DIFFRACTION 100.0
5JJ8 LYASE 04/22/16 Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa - alternate crystal packing form Pseudomonas aeruginosa 2.585 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 387 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004326 (477 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_61860

Human Homologs

References

No references are associated with this feature.