Pseudomonas aeruginosa UCBPP-PA14, PA14_63350

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_63350
Name
Replicon	chromosome
Genomic location	5652879 - 5653361 (+ strand)
Transposon Mutants	1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs	2 transposon mutants in orthologs

Cross-References

RefSeq	YP_793258.1
GI	116052941
Entrez	4383243
INSDC	ABJ14177.1
NCBI Locus Tag	PA14_63350
UniParc	UPI0000396E9F
UniProtKB Acc	Q02FM8
UniProtKB ID	Q02FM8_PSEAB
UniRef100	UniRef100_Z2DM12
UniRef50	UniRef50_A4XQ89
UniRef90	UniRef90_A6VCQ3

Product

Feature Type	CDS
Coding Frame	1
Product Name	GNAT family acetyltransferase
Synonyms
Evidence for Translation
Charge (pH 7)	0.86
Kyte-Doolittle Hydrophobicity Value	-0.134
Molecular Weight (kDa)	17.8
Isoelectric Point (pI)	7.50

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4M3S	TRANSFERASE	08/06/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with HEPES	Pseudomonas aeruginosa	1.3	X-RAY DIFFRACTION	99.4
3KKW	TRANSFERASE	11/06/09	Crystal structure of His-tagged form of PA4794 protein	Pseudomonas aeruginosa PAO1	1.41	X-RAY DIFFRACTION	99.4
4KOS	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefmetazole	Pseudomonas aeruginosa	1.55	X-RAY DIFFRACTION	99.4
4KOW	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefoxitin	Pseudomonas aeruginosa	1.45	X-RAY DIFFRACTION	99.4
4KOU	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefixime	Pseudomonas aeruginosa	1.6	X-RAY DIFFRACTION	99.4
4KOV	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefuroxime	Pseudomonas aeruginosa	1.6	X-RAY DIFFRACTION	99.4
4L89	TRANSFERASE	06/16/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with covalently bound CoA	Pseudomonas aeruginosa	1.6	X-RAY DIFFRACTION	99.4
5VDB	transferase/transferase inhibitor	04/01/17	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 3	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.4	X-RAY DIFFRACTION	99.4
4KUA	TRANSFERASE	05/21/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794	Pseudomonas aeruginosa	1.5	X-RAY DIFFRACTION	99.4
4KUB	TRANSFERASE	05/21/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with CoA	Pseudomonas aeruginosa	1.57	X-RAY DIFFRACTION	99.4
4OAD	TRANSFERASE	01/04/14	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with chloramphenicol	Pseudomonas aeruginosa	1.45	X-RAY DIFFRACTION	99.4
4KLV	TRANSFERASE	05/07/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 4-methylumbelliferyl phosphate	Pseudomonas aeruginosa	1.3	X-RAY DIFFRACTION	99.4
4KOR	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 7-aminocephalosporanic acid	Pseudomonas aeruginosa	1.25	X-RAY DIFFRACTION	99.4
4L8A	TRANSFERASE	06/16/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA	Pseudomonas aeruginosa	1.2	X-RAY DIFFRACTION	99.4
5VD6	transferase/transferase inhibitor	04/01/17	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with bisubstrate analog 6	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	1.2	X-RAY DIFFRACTION	99.4
4OAE	TRANSFERASE	01/04/14	Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol	Pseudomonas aeruginosa	1.25	X-RAY DIFFRACTION	97.5
4KOY	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cephalosporin C	Pseudomonas aeruginosa	1.4	X-RAY DIFFRACTION	99.4
4KLW	TRANSFERASE	05/07/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with 2-(aminocarbonyl)benzoate	Pseudomonas aeruginosa	1.3	X-RAY DIFFRACTION	99.4
4KOX	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefalotin	Pseudomonas aeruginosa	1.8	X-RAY DIFFRACTION	99.4
3PGP	TRANSFERASE	11/02/10	Crystal structure of PA4794 - GNAT superfamily protein in complex with AcCoA	Pseudomonas aeruginosa	1.42	X-RAY DIFFRACTION	99.4
4KOT	TRANSFERASE	05/12/13	Crystal structure of a GNAT superfamily acetyltransferase PA4794 in complex with Cefotaxime	Pseudomonas aeruginosa	1.55	X-RAY DIFFRACTION	99.4

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 20 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG004432 (386 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_63350 Search term: GNAT family acetyltransferase

Human Homologs

References