Pseudomonas aeruginosa M18, PAM18_0340 (thyA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0340
|
| Name |
thyA
|
| Replicon | chromosome |
| Genomic location | 378274 - 379068 (+ strand) |
Cross-References
| RefSeq | YP_005972931.1 |
| GI | 386056409 |
| Entrez | 12564358 |
| NCBI Locus Tag | PAM18_0340 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
thymidylate synthase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -3.24 |
| Kyte-Doolittle Hydrophobicity Value | -0.154 |
| Molecular Weight (kDa) | 30.0 |
| Isoelectric Point (pI) | 6.51 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 401 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000334 (395 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0340
Search term: thyA
Search term: thymidylate synthase
|
Human Homologs
|
Ensembl
110, assembly
GRCh38.p14
|
thymidylate synthetase [Source:HGNC Symbol;Acc:HGNC:12441]
E-value:
3.9e-80
Percent Identity:
51.4
|
References
No references are associated with this feature.