Pseudomonas aeruginosa M18, PAM18_0692 (rpoA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0692
|
| Name |
rpoA
|
| Replicon | chromosome |
| Genomic location | 737524 - 738525 (+ strand) |
Cross-References
| RefSeq | YP_005973283.1 |
| GI | 386056761 |
| Entrez | 12564721 |
| NCBI Locus Tag | PAM18_0692 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
DNA-directed RNA polymerase subunit alpha
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -15.59 |
| Kyte-Doolittle Hydrophobicity Value | -0.249 |
| Molecular Weight (kDa) | 36.6 |
| Isoelectric Point (pI) | 4.62 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 7F0R | TRANSCRIPTION/DNA | 06/06/21 | Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1); SYNTHETIC CONSTRUCT | 5.8 | ELECTRON MICROSCOPY | 100.0 |
| 7XYA | TRANSCRIPTION | 06/01/22 | The cryo-EM structure of an AlpA-loading complex | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 3.3 | ELECTRON MICROSCOPY | 100.0 |
| 7XYB | TRANSCRIPTION | 06/01/22 | The cryo-EM structure of an AlpA-loaded complex | Pseudomonas aeruginosa; SYNTHETIC CONSTRUCT | 3.7 | ELECTRON MICROSCOPY | 100.0 |
| 7VF9 | TRANSCRIPTION | 09/10/21 | Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes | Pseudomonas aeruginosa PAO1 | 4.04 | ELECTRON MICROSCOPY | 100.0 |
| 7XL4 | TRANSCRIPTION | 04/21/22 | Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (closed lobe) | Pseudomonas aeruginosa PAO1 | 3.86 | ELECTRON MICROSCOPY | 100.0 |
| 7XL3 | TRANSCRIPTION | 04/21/22 | Cryo-EM structure of Pseudomonas aeruginosa RNAP sigmaS holoenzyme complexes with transcription factor SutA (open lobe) | Pseudomonas aeruginosa PAO1 | 3.13 | ELECTRON MICROSCOPY | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001472 (536 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0692
Search term: rpoA
Search term: DNA-directed RNA polymerase subunit alpha
|
Human Homologs
References
No references are associated with this feature.