Pseudomonas aeruginosa M18, PAM18_0803
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_0803
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 883022 - 884230 (+ strand) |
Cross-References
| RefSeq | YP_005973392.1 |
| GI | 386056870 |
| Entrez | 12564831 |
| NCBI Locus Tag | PAM18_0803 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
putative major facilitator superfamily transporter
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 13.88 |
| Kyte-Doolittle Hydrophobicity Value | 0.962 |
| Molecular Weight (kDa) | 41.8 |
| Isoelectric Point (pI) | 9.67 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AMR gene predictions from CARD database
Identified using the Resistance Gene Identifier (RGI)
| Model Name | Definition | Accession | Model Type (?) | SNP | Cutoff | Bit Score | Percent Identity | CARD Version |
| bcr-1 | Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene. [PMID:25085655, PMID:26093374] | ARO:3003801 | protein homolog model | Perfect | 758.1 | 100.0 | 3.2.5 |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 569 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001563 (351 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_0803
Search term: putative major facilitator superfamily transporter
|
Human Homologs
References
No references are associated with this feature.