Pseudomonas aeruginosa M18, PAM18_2012

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_2012
Name
Replicon chromosome
Genomic location 2208845 - 2209792 (- strand)

Cross-References

RefSeq YP_005974600.1
GI 386058078
Entrez 12566054
NCBI Locus Tag PAM18_2012

Product

Feature Type CDS
Coding Frame 1
Product Name
putative lipase
Synonyms
Evidence for Translation
Charge (pH 7) -2.10
Kyte-Doolittle Hydrophobicity Value -0.028
Molecular Weight (kDa) 34850.8
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6I8W HYDROLASE 11/21/18 Crystal structure of a membrane phospholipase A, a novel bacterial virulence factor Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 503 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000798 (2691 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_2012
Search term: putative lipase

Human Homologs

Ensembl 110, assembly GRCh38.p14
epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760]
E-value: 9.0e-15
Percent Identity: 24.8
Ensembl 110, assembly GRCh38.p14
epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760]
E-value: 9.0e-15
Percent Identity: 24.8
Ensembl 110, assembly GRCh38.p14
epoxide hydrolase 3 [Source:HGNC Symbol;Acc:HGNC:23760]
E-value: 9.0e-15
Percent Identity: 24.8

References

No references are associated with this feature.