Pseudomonas aeruginosa M18, PAM18_2573 (foxA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa M18
GCF_000226155.1|latest |
| Locus Tag |
PAM18_2573
|
| Name |
foxA
|
| Replicon | chromosome |
| Genomic location | 2813737 - 2816199 (+ strand) |
Cross-References
| RefSeq | YP_005975158.1 |
| GI | 386058636 |
| Entrez | 12566623 |
| NCBI Locus Tag | PAM18_2573 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
Ferrioxamine receptor FoxA
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -25.45 |
| Kyte-Doolittle Hydrophobicity Value | -0.425 |
| Molecular Weight (kDa) | 90.0 |
| Isoelectric Point (pI) | 4.77 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
PDB 3D Structures
| Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
| 6I96 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa in complex with ferrioxamine B | Pseudomonas aeruginosa | 1.85 | X-RAY DIFFRACTION | 100.0 |
| 6Z8A | MEMBRANE PROTEIN | 06/02/20 | Outer membrane FoxA in complex with nocardamine | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 2.95 | X-RAY DIFFRACTION | 100.0 |
| 6I97 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa in complex with ferrioxamine B and a C-terminal TonB fragment | Pseudomonas aeruginosa | 3.35 | X-RAY DIFFRACTION | 100.0 |
| 6I98 | MEMBRANE PROTEIN | 11/22/18 | Structure of the ferrioxamine B transporter FoxA from Pseudomonas aeruginosa, apo state | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 100.0 |
| 8B43 | MEMBRANE PROTEIN | 09/19/22 | Crystal structure of ferrioxamine transporter | Pseudomonas aeruginosa | 2.49 | X-RAY DIFFRACTION | 100.0 |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 302 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000149 (2669 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAM18_2573
Search term: foxA
Search term: Ferrioxamine receptor FoxA
|
Human Homologs
References
No references are associated with this feature.