Pseudomonas aeruginosa M18, PAM18_3633 (pykF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa M18
GCF_000226155.1|latest
Locus Tag
PAM18_3633
Name
pykF
Replicon chromosome
Genomic location 4039577 - 4041010 (+ strand)

Cross-References

RefSeq YP_005976216.1
GI 386059694
Entrez 12567687
NCBI Locus Tag PAM18_3633

Product

Feature Type CDS
Coding Frame 1
Product Name
pyruvate kinase
Synonyms
Evidence for Translation
Charge (pH 7) -5.41
Kyte-Doolittle Hydrophobicity Value -0.043
Molecular Weight (kDa) 51.5
Isoelectric Point (pI) 5.76

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7OO1 TRANSFERASE 05/26/21 Structure, function and characterization of a second pyruvate kinase isozyme in Pseudomonas aeruginosa. Pseudomonas aeruginosa PAO1 3.01 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 614 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001412 (474 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAM18_3633
Search term: pykF
Search term: pyruvate kinase

Human Homologs

Ensembl 110, assembly GRCh38.p14
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 1.1e-77
Percent Identity: 39.4
Ensembl 110, assembly GRCh38.p14
pyruvate kinase M1/2 [Source:HGNC Symbol;Acc:HGNC:9021]
E-value: 1.1e-77
Percent Identity: 39.4

References

No references are associated with this feature.